The Neurobiology of Obsessive-Compulsive Disorder

December 17, 2022March 27, 2023 by Rebecca

OCD Brain: What Research Tells Us.

Obsessive-compulsive disorder (OCD) is a common mental disorder that is characterized by unwanted, intrusive thoughts (obsessions) and repetitive behaviors (compulsions) that individuals feel compelled to perform. The exact cause of OCD is not fully understood, but research suggests that abnormalities in certain brain circuits and the serotonin may play a role in the development of OCD. This blog references research and studies focused on the brain and OCD.

One study published in the journal Nature Communications used functional magnetic resonance imaging (fMRI) to examine the brain activity of individuals with OCD. The study found that OCD is associated with abnormal activity in parts of the brain regions involved in processing information related to habits and routines. The researchers also found that this abnormal activity was correlated with the severity of OCD symptoms.

Another study, published in the journal Neuropsychopharmacology, found that individuals with OCD had reduced levels of serotonin in the brain region that is involved in decision-making and impulse control. The researchers also found that the severity of OCD symptoms was correlated with the degree of serotonin deficiency in this brain region.

It is important to note that OCD is a complex disorder and likely involves multiple factors, including genetic and environmental influences. Further research is needed to fully understand the underlying causes of OCD and to develop effective treatments for this condition. There are current treatment options available for OCD and these treatment options will expand as research develops.